Taking testosterone replacement therapy can raise your risk of blood clots. This can lead to problems such as strokes and heart attacks. Your healthcare team will have you perform regular blood tests, called the complete blood count (CBC), to check that your blood cell counts are in the safe range. Get emergency help right away if you have chest pain, cold sweats, left arm pain, difficulty breathing, trouble walking, trouble speaking, or weakness on one side of the body, since you might have to stop taking the medication.

Testosterone enanthate might raise the risk for enlarged prostate and prostate cancer in males. Symptoms include pain, inability to urinate or change in the amount of urination, and blood in the urine. If you notice any of these symptoms, talk to your prescriber right away before it becomes worse.

Testosterone enanthate is a controlled substance because it has a risk of misuse and dependency, especially if you use higher doses than prescribed or use it with other testosterones.

Using testosterone enanthate for long periods of time can cause life-threatening liver problems. Your HCP will order blood tests to check your liver enzymes to make sure they’re not getting too high. Let your care team know if you’re experiencing stomach pain, light-colored stools, dark urine, or if your skin or the whites of your eyes turn yellow because you might need to stop the medication.